I always backup with DVD43 then Nero Recode 2 unless it's a Sony disc then I use DVDFAB Decrypter. So most of the time all I need is DVD43. Here are a few I backed up with DVD43 sucessfully Devil's Rejects,Charlie and the Chocolate Factory,Dukes of Hazzard,Cinderella Man,Skeleton Key,Mr and Mrs Smith,March of the Penguins,Polar Express.
I've used DVD43 a couple of times, but found AnyDVD to be much better, as it is updated a lot more often. Slysoft is always on top of things. As soon as a new encryption emerges, they're there to find a way around it.
I have contemplated purchasing AnyDVD, But just decrypted 5 new DVD releases with just DVD43 and Nero Recode2 and not a single problem. My blank media of choice is SONY 8x -R/+R which have had added to my great results. I also will agree you can never have too many decryption software programs so if you can afford to purchase them so be it. AnyDVD is not out of the question but for now DVD43 does the trick for me.